This investigation describes the long-term benefits of guided tissue regeneration with barrier membranes in a population of 175 patients with severe intrabony defects and treated in a periodontal private practice. These data describe the long-term outcomes of a patient cohort who had been attending a periodontal maintenance program with various levels of compliance. In the analyses...

Patient Characteristics The experimental population consisted of 175 patients with one GTR treated defect included. Average age was 44.5 ± 10.2 (range 18 to 76 years), 43% were males, and 32% were current smokers. Before GTR surgery, the baseline full-mouth plaque and bleeding scores (FMPS, FMBS) were 13.9% ± 6.5% and 10.5% ± 3.7%, respectively; 1 year later they were 9.6% ± 3.7% (FMPS range ...

Study Population and Design One-hundred seventy-five patients included in the authors’ database of GTR treated sites from previously published investigations were selected to participate in this study by identifying cases presenting for periodontal maintenance over a 4-month period between February and May 2002. All subjects had previously received comprehensive periodontal treatment including ...

Periodontal regeneration has been a clinical reality for at least 2 decades. Recent meta-analyses of randomized controlled clinical trials indicated that at least two periodontal regenerative approaches, the application of barrier membranes and the application of enamel matrix proteins, provide significant additional benefits for the treatment of intrabony defects as compared to access flap alone....

Background: The longevity of the clinical benefits of guided tissue regeneration (GTR) has not been fully explored. The aim of this investigation was to assess the long-term survival of GTR treated sites in terms of clinical attachment level (CAL) stability and tooth loss. Methods: A total of 175 patients with one deep intrabony defect were selected for a retrospective investigation of tooth rete...